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VirusTaxo
Predict taxonomic classification of DNA, RNA Viruses from genome sequences
Get Started
Add VirusTaxo in LatchBio
  1. 1. Log into https://latch.bio.
  2. 2. Find VirusTaxo within Explore tab or, click here.
  3. 3. Add VirusTaxo to your workspace (There's a button for it).
  4. 4. Go to Workflows tab and click on VirusTaxo.
Provide Input Options and Run
  1. 1. Provide input fasta file. You can upload fasta file containing viral genome (single or multiple) sequences. Or, you can use test input fasta file containing 1,553 SARS-CoV-2 genome sequences provided by us. Download from here.
  2. 2. Select Genome Type as RNA since SARS-CoV-2 is an RNA virus.
    If you do not know what the genome type is, select Unknown option. In case of DNA viruses, select DNA.
  3. 3. Launch the workflow.
Description
For taxonomic classification of viruses from metagenomic sequences, we developed VirusTaxo using diverse (e.g., 402 DNA and 280 RNA) genera of viruses. VirusTaxo has an average accuracy of 93% at genus level prediction in DNA and RNA viruses. VirusTaxo outperformed existing taxonomic classifiers of viruses where it assigned taxonomy of a larger fraction of metagenomic contigs compared to other methods. Benchmarking of VirusTaxo on a collection of SARS-CoV-2 sequencing libraries and metavirome datasets suggests that VirusTaxo can characterize virus taxonomy from highly diverse contigs and provide a reliable decision on the taxonomy of viruses.
How to Cite
Rajan Saha Raju, Abdullah Al Nahid, Preonath Chondrow Dev, Rashedul Islam. VirusTaxo: Taxonomic classification of virus genome using multi-class hierarchical classification by k-mer enrichment. Genomics (2022), PMID:35718090 DOI:10.1016/j.ygeno.2022.110414.